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The gear ratios were a lot different. The M20 wide ratio had a 2.52:1 first gear ratio, which helped the small blocks get off the line better. The big blocks and stronger small blocks didn't need as steep a first gear ratio, so the close ratio transmissions started out with a 2.20:1 first gear. That's pretty tall. That's like starting off in second gear on any modern manual transmission car. But shifting gears would put the engine at the same rpm better, and the gear ratios were better separated for performance driving.
The rock crusher M22 had "straight cut" gears (still helical, but at a shallower angle), and was noisier, but definitely handled much more torque. You can still find M22's at swap meets, and they go for about $1200 to $1400 bucks as far as I've seen. Not too many takers at that price. But I do see them every time I go to a good swap meet.
You could make an M20 or M21 stronger too, (Doug Nash 5-speed as well) if you modified it by removing the synchros. That was done on drag cars a lot.
Yes, your M20/M21 will last with a stroker small block or big block, up to a point. They were optioned on big blocks too. They can handle very decent torque.
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