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I replaced mine when i bought my car, just to be on the safe side. I changed out most of the oils and liquids so there would be no doubts of when they were changed. Coolant wise i run DEX-COOL.
Even though GM says Dexcool is good for 5 years, I never let my coolant go more than 2 years without refreshing it... I do not flush the whole system, just drain the 2 gallons or so that will come out through drain plug and refill with 50/50 mixture...