When you click on links to various merchants on this site and make a purchase, this can result in this site earning a commission. Affiliate programs and affiliations include, but are not limited to, the eBay Partner Network.
I'm no expert but I would think that it could be potentially unsafe to run different types of tires on a car that was not used for special applications (e.g, drag racing). I'm thinking about the guys years ago who used to run snow tires in the back (because of RWD) and normal tires in front and end-up sliding into something because the front tires did not grab. Maybe not the best analogy but I personally could see problems in certain conditions (say wet streets) where the run flats might tend to slip and some nicer tires in the rear would just keep gripping.
runflats are stiffer. By mixing the types, it has the same effect as having a stiffer spring rate up front. I always mix this up, but I think that makes the car understeer more.
I bought my car used and it came with run flats out back but non run flats up front. I notice that the run flats get hotter, as their pressure ends up being 2psi higher on the highway. All four tires start out at the same psi on the DIC, but on the highway after a long drive the fronts end up at 35 while the backs end up at 37. So that runflat technology comes at the price of hotter tire temps.
Asking for trouble... You won't be happy with handling or ride. May be OK for putting slicks on at the drags, but first high speed turn you hit, get a good grip and hang on!
Why though? Let's be honest, how many of us are going to push our cars to the absolute limits? And even if we do, as long as we know the handling characteristics of our cars, having different tires from front to back won't hurt us. It's not like the car is just going to suddenly go into a 360 spin due to different tires.
I've owned many high performance cars, and many times have run totally different tires on the back compared to the front. I even owned one car where I ran bias plies on the back (cheater DOT "slick type" tires) and skinny radials up front, and never had a problem. I knew where it's limits were, and respected them.
So I seriously doubt anyone on here will have a problem running non run flats on one end and run flats on the other. Just know your cars limits and don't go beyond them and you'll be fine.
Look at it another way, these cars come with 245s up front and 275s out back, so that alone will create slightly different handling characteristics too, but it obviously still works well.