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I put in NGK copper core V groove plugs and taylor spiral pro wires on my C5. Pretty simple job (u-hoint sparkplug socket head helps) - just make sure to take it easy (no cross threading!), use anti-seize on plug threads sparingly, and dielectric grease (small amount) in spark plug wire ends to keep from sticking.
Corvette faq site has some tips, and check the forums tech tips section (under the Other banner at top). You will find lots of opinions - myself, when removing the platinum tip plugs and finding 2 of 8 without the platinum tip, decided to just go simple, low cost, and good performance!
I went with the NGK tr-55 Coppers like so many others here - But After seeing different wires at shows - THE wire to have seems like the Taylor Thundervolt - it is a 10 mm wire - I know, the actual performance gain you will see from a 10mm wire over a 7 or 8 is negligable - BUT the look of the 10mm is FAR better than any 7 or 8 - That beefy wire just looks great. Also the Taylors have a very high heat rating and are great on cars with headers where the wire is right next to the header.
AC Iridium, best plug for a LS-1/6 I'm told, that's what I went with.
This is a topic of hot debate but I really beleive that iridium has passed up copper now that each pjug gets such a wallop from individual coil packs. It also had the added avantage of very long life. Here is what the tech editor from Road and Track said:
From Road and Track Technical Correspondence September 2004:
"Sparkplug electrode material does not play a direct role in spark intensity. However, platinum and iridium electrodes can be much smaller, notably reducing misfiring because they result in more robust flame kernels. This is because the smaller electrodes are less of a shroud, exposing more mixture to the flame front.
An unusually dramatic illustration of this is with aftermarket supercharged engines running high boost. Such engines often falter terribly at high boost and high rpm due to ignition failure. Simply screwing in iridium-tipped sparkplugs typically eliminates the misfiring and allows the engine to rev to its power peak. In practice, this means a simple plug change is worth 30 bhp simply because the new plugs allow the engine to reach its designed redline."