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You will need the following items in addition to the radio:
1) GPS antenna
2) Nav data DVD
3) Post-install trip to the GM Dealer to have him perform a "VIN Relearn" to match the used NAV radio that you are installing to your particular car. The newly-installed used radio will lock upon 1st startup in your car, and this procedure 'unlocks' it and 'marries' it to your new host vehicle.
Other than that, it should be a direct plug-and-play swap.
Is this as straight forward if I do not have the Bose system? I have an 08 coupe with the base model stereo. I also woud like to upgrade to factory nav. (I thought I had heard this was a bit more challenging if I don't have the Bose system to start.)