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06 with NAV and original battery lasted 38,000 miles. It was still good when I replaced it but I did not want to press my luck. Not counting the earlier problems with the 05 manual Vettes, I think most people who have problems are ones that do not put many miles on their cars or have added electrical mods that have a parisitic drain. Of course there is always exceptions.
06 with MN6, no onstar but all other options including Ipod interface and radar detector. No problems with Nav or HUD either. 4+ years on OEM battery never a problem with car sitting for up to 6 weeks. Replaced OEM battery in Oct with Red Top and no starting or battery problems... ever with this car. Car is on battery tender over the winter....
06 (bought new in July 06). Had batterey problems starting in late August 06, dealer replaced in Oct 06, no problems since. Keep both my Vettes on battery tender for winter storage (Nov thru Mar).
06 bought two years ago with 9,000 miles. It already had an aftermarket battery when purchased. This past Monday the Sirius SIR-GM1 converter just all of a sudden went dead. [I do not like XM]. Radio still worked fine. Next day, battery dead. Charged it and it was dead again the next day. The car now has a new NAPA battery. Car is a 3LT with navi. I could not find a dedicated fuse link for the satellite receiver so I disconnected it and ordered a new one after Sirius customer service could not get the existing one to reactivate!