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Some of the early cars used Rolls Royce aircraft engines. They were 16 litres and I believe 12 cylinders. If you want to get picky and consider more than one engine, Tommy Ivo a drag racer in the late 60's had a car with 4 Buick engines that equalled almost 1400 Cubic inches. Many weird combinations out there.
The Rolls Royce Griffon displaced 2240 C.I. but that's nothing compared to a Pratt & Whitney R-4360 (yes, 4360 C.I.) radial engine but you would be hard pressed to fit that in a car.
The Rolls Royce Griffon displaced 2240 C.I. but that's nothing compared to a Pratt & Whitney R-4360 (yes, 4360 C.I.) radial engine but you would be hard pressed to fit that in a car.