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I also had this problem with the adjustement **** on the regulator hitting the back edge of the plenum. I took a dremel too the plenum to give it some extra clearance.
Take a dremel to the plenum and you should be fine.
My Holley just clears. I adjusted fuel pressure before I installed plenum. Maybe once you have adjusted it, there will be clearance. Mine is set for 43lbs with no vacuum and I have about 3/32" clearance.
:cheers: