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I have the A4 in a 2001 coupe. It seems fine. I've never driven a C6 with the six speed auto. I can't really compare. What you intend to use the car for may help you decide. If you are a track guy, I'd get a Manual 6....if I was just a "cruising" guy with a little spirited driving now and then...the A4 or A6 would be fine. It's a fast car no matter what the tranny is in it.
I have had a 07 automatic (6 spd) and now a 97 automatic (4 spd). My personal preferance is for the 4 spd. My 07 with my driving style (weekends, shows, just enjoyment) didn't have the instant response I feel in the 97 (probably a matter of degrees though). It would hunt thru the gears occasionaly as well (but my driving style may have been partly to blame). Drive both I say and try to drive them the way you anticipate the vette being used, if you drive aggressivly, you may like the 6spd better than I did, if you drive relaxed as my style normally was, you may lean towards the 4spd..............but either way, I assure you, you will like them!