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That is where I am right now. Mine was running rough with a P0300 code. I pulled in the garage and did the same thing as you, pulling wires off and listening for a change in the idle and not really noticing any. I had logged with HPTuners, so I went in the house to go over that.
A couple of days later, I was going to change the oil in another vehicle. It was cold and rainy so I decided to back the vette out of the garage and pull the other vehicle in to change the oil in it. Well, it wouldn't start, no starter, nothing, just the lights came on. Really strange since I had started and stopped it several times when I parked it. I checked the codes and had a crank sensor code. I bought a crank sensor today, but didn't get a chance to put it in. I'll post back and let you know the results.
If all else fails, you can go back to the old school and hook up a vacuum gauge. Look at it during idle:
1) reads very low, you have a leak
2) reads low and steady, late ignition (which you should see with HPTuner)
3) reads high and steady, early ignition (same as above)
4) neddle fluctuates as engine speed increases, ignition miss or valve spring
5) gradual drop in reading at idle, excessive back pressure
6) intermittent fluctuation at idle with good vacuum, ignition miss
7) stead from 17-22 in Hg, your are right on!
Just some ideas to look at, there might be more ways to interpret a vacuum gauge, but that is all I can think of...