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Now, young man, just pick a stock E85 tune from those GM vechiles that are E85 capable. You know where the repository is, right? :-)
Do they still have IAT spark reduction based on how hot the air is?
If so, why?
Spraying meth does of course lower intake temps.
And add fuel.
Which all leads us to a tuning strategy. I.e. how to deal with E85 and meth injection in various situations.
There is only one table to adjust timing based on IAT, so it doesn't change based on E content. Whether that means it should or COULD be different or not is anyone's guess. My guess is if GM designed a E85 specific IAT timing table they would make it much less intrusive that the one they include from the factory
On ethanol you can usually just tune to MBT timing (Maximum Brake Torque) without running into detonation. So use a dyno and turn the timing up until it stops gaining or starts to lose power. Unless you have a pretty wild setup, you shouldn't run into detonation before reaching MBT. I have ~10.25 CR and run 15psi with a ZR1 blower and MBT on E98 was 24* if I remember correctly. It has the same on E85, just use the E98 for when I am really beating on it and spraying all the nitrous. Timing is pulled for the nitrous though. Think 3-4* per 100hp can't remember. Sometimes tuning to MBT isn't always the best way to go though, for example when you are really pushing the stock bottom end stuff.
This is super interesting. I did not realize E85 was quite THAT good. good information.
In case of running out of injectors, you can always add meth.
It is of course another variable, but if you don't trust meth kit, why did you install it anyway?
So all in all; it depends what fuel injectors you have now. And how reliable you want to have your particular combination. I myself do not trust meth systems, unless tested and serviced each spring.